KEGG pathway enrichment analysis was performed to screen potential targets and the results indicated that ginsenoside Rb1 modulates atherosclerosis development by multiple proliferation-related pathways, such as PI3K-Akt signaling pathway, thyroid hormone signaling pathway, proteoglycans in cancer, and AGE-RAGE signaling pathway in diabetic complications (Figure 4D). Here, AKT1 is linked to atherosclerosis.