PIGA and Familial adenomatous polyposis: Differential transcriptional activity, indicating altered cellular processes, was assessed in matched WES and WTS data from 20 duodenal adenomas (n = 10 FAP and n = 10 MAP) stratified into those with PIGA somatic coding mutations (n = 7, 3 FAP, 4 MAP) and those without (n = 13, 6 FAP, 7 MAP).