PDCD1 and cancer: Table 4 represents the calculated FPRP values for the main evident findings in this meta-analysis. With the assumption of a prior probability of 0.25, the FPRP values were less than 0.2, implying the observed correlations were significant. The heterozygote model of PD-1.3 was related to cancer risk, as well as the allele model of PD-L1 rs4143815. Similarly, with a prior probability of 0.25, the allele, homozygote, dominant and recessive models of PD-L1rs17718883 was notably associated with cancer risk (P < 0.2, Table 4).