CD274 and hepatocellular carcinoma: As for PD-L1 rs2297136, the mutant was closely related to NSCLC (C vs. G: OR = 1.30, 95% CI = 1.00-1.70, P = 0.048; GC vs. GG: OR = 2.29, 95% CI = 1.56-3.36, P = 0.000; CC+GC vs. GG: OR = 2.09, 95% CI = 1.43-3.04, P = 0.000; CC vs. GG+GC: OR = 0.44, 95% CI = 0.20-0.97, P = 0.042) and HCC risk (C vs. G: OR = 0.68, 95% CI = 0.49-0.93, P = 0.017; CC vs. GG: OR = 0.39, 95% CI = 0.18-0.85, P = 0.018; GC vs. GG: OR = 0.24, 95% CI = 0.12-0.48, P = 0.000; CC+GC vs. GG: OR = 0.19, 95% CI = 0.10-0.37, P = 0.000; CC vs. GG+GC: OR = 0.08, 95% CI = 0.01-0.60, P = 0.014, Supplementary Table 3).