Similarly, CLIC5 expression was found to be lower than that of normal kidney tissues in renal clear cell carcinoma tissues extracted from our research center, while MXD3, NUF2, PABPC1L, and PLK1 were significantly higher in renal clear cell carcinoma tissues than in normal kidney tissues (Figure 8C, 8D). The gene discussed is CLIC5; the disease is clear cell renal carcinoma.