The results of the TCGA-KIRC cohort showed that either in paired or unpaired renal cancer tissues, except for CLIC5, which was in a low expression state, the remaining four genes (MXD3, NUF2, PABPC1L, and PLK1) were in a high expression (Figure 8A, 8B). The gene discussed is PLK1; the disease is renal carcinoma.