TYRO3 and gastric cancer: In 2010, the randomized ToGA trial was able to show that patients with gastric cancer and human epidermal growth facter receptor 2 (HER2) protein overexpression had beneficial effects of therapy consisting of chemotherapy and HER2‐specific blockade through monoclonal antibody trastuzumab7 One family of RTKs is the TAM receptor (TAMR) family, comprising MerTK, Axl, and Tyro3, all of which share a similar structure.