Baek et al. (2018) isolated triterpenoids from the methanol extract of I. obliquus to assess its cytotoxic effects on four human lung adenocarcinoma cell lines, each one with a different p53 tumor protein conditions (human lung adenocarcinoma cell lines A549, H1264, H1299, and Calu-6). Here, TP53 is linked to lung adenocarcinoma.