The GABA-T and MAO-A inhibitory properties of RelissaTM are of particular interest for its applications in low-mood states and associated conditions such as sleep disorders, which are intricately interconnected with emotional distress, reflecting a bidirectional relationship that has been extensively documented in scientific literature (Philbrook and Macdonald-Gagnon, 2021; Yasugaki et al., 2023). The gene discussed is MAOA; the disease is sleep disorder.