To determine whether MyD88 would also be required for LTX-315 to induce maturation of TiDCs, WT and MyD88-/- mice bearing B16 melanomas were treated with intratumoral LTX-315, using FITC-OVA as a fluorescence tracer to track DC migration from melanoma tissues to dLNs (Figure 6A). Here, MYD88 is linked to melanoma.