ITGAX and melanoma: Consistent with the results of previous experiments (Figure 1), intratumoral LTX-315 treatment resulted in the maturation of TiDCs, as evidenced by an increase of CD11c+ DCs, FITC+ DCs, pDCs, and cDCs in dLNs (Figures 6B-E) coupled with a decrease of TiDCs (particularly cDCs) in the melanoma tissues in wild-type mice (Figures 6F, G).