WDR59 and atherosclerosis: One member of this class, miR-103, is known to increase the susceptibility of proliferating endothelial cells to mitotic aberrations induced by oxidized low-density lipoprotein through targeted expression of long chain, non-coding RNA WDR59, promoting vascular inflammation and atherosclerosis.17 Tang et al.18 analyzed 126 patients with AIS and found that upregulation of miR-103 expression was associated with the degree of neurological impairment and deterioration of neurological function.