In this study, the effect of the association of blood group antigens with the interleukin (IL)-6 gene in the inflammatory process on cardiovascular disease formation and longevity is explained.24 In our study, when the average age groups were taken, it was determined that the O Rh D+ and AB Rh D+ groups were younger than the B Rh D+ and AB Rh D- groups. Here, RHD is linked to cardiovascular disorder.