TPD52 and familial pancreatic carcinoma: Cox regression multivariate analysis showed that low differentiation of pancreatic cancer, TNM III-IV stage, high expression of TPD52 and low expression of miR-133a were independent risk factors affecting the prognosis of pancreatic cancer patients, which further confirmed that detecting the expression levels of TPD52 and miR-133a in pancreatic cancer tissues can predict the prognosis of pancreatic cancer patients and is expected to provide new targets for the treatment of pancreatic cancer.