TPD52 and metastatic malignant neoplasm in the lymph nodes: Kaplan-Merier survival analysis showed that lymph node metastasis, peripancreatic nerve invasion, tumor tissue differentiation, TNM staging and expression levels of TPD52 and miR-133a were all risk factors affecting the survival and prognosis of patients with pancreatic cancer (P<0.05), as shown in Table-III.