For example, METTL3, VIRMA, FTO, and IGF2BP1 aberrant expression linked to breast cancer, METTL3, FTO, and YTHDF1 disrupted expression promotes lung cancer, and METTL3/14, FTO, and YTHDF2 dysregulated expression promotes acute myeloid leukemia (23). This evidence concerns the gene METTL3 and acute myeloid leukemia.