Regulates lipid and cholesterol production by inhibiting sterol regulatory element binding proteins (SREBP)1 and 2. Downregulates fatty acid synthase (FASN) and 3hydroxy3methylglutaryl CoA reductase (HMGCR) in prostate cancer cell lines, inhibiting cell growth, migration, and invasion. The gene discussed is HMGCR; the disease is prostate carcinoma.