RELA and ependymoma: In other cases, supratentorial ependymomas may present ZFTA fusions with gene partners that differ from RELA, such as NCOA1/2, MAML2, and MN1. These cases also show significant histopathological heterogeneity and lack pathological activation of NF-κB signaling (Tauziède-Espariat et al., 2021).