MYCN and neoplasm: According to 2021 WHO Classification of CNS Tumors, the spinal location has been recognized three types of ependymomas: (1) spinal ependymoma (morphologically similar to other ependymomas); (2) MYCN-amplified spinal ependymoma (characterized by MYCN-amplification and poorer prognosis); (3) myxopapillary ependymoma (identifying morphological features and usually localized in conus medullaris/filum terminale) (WHO Classification of Tumours Editorial Board, 2021).