In addition, isolated cases of MYC methylation class AT/RT and WNT-activated medulloblastoma have been shown to present EZHIP positivity, but this was only focal (<1% of positive tumor cells), and thus, this was not to considered as true EZHIP overexpression (>90% of positive tumor cells) (Antin et al., 2020). The gene discussed is EZHIP; the disease is medulloblastoma.