Topical application of the selective ARβ1 agonist dobutamine hydrochloride (DOB) to IMQ‐treated mice aggravated psoriasis‐like manifestations and promoted γδT‐cell IL‐17A production in skin (Figure S6a–d, Supporting Information); application of the selective ARβ1 antagonist acebutolol hydrochloride (ACE) had the opposite effects (Figure S6e–g, Supporting Information). This evidence concerns the gene IL17A and psoriasis.