TH, the rate‐limiting enzyme in the biosynthesis of catecholamines, including dopamine, norepinephrine, and epinephrine, was used to identify the sympathetic nerves in skin.[34] The over‐activation of TH by Ser40‐phosphorylation is a key marker of SNS hyperactivation.[37] The positive linear correlation between TH and CAMK2G expression in human neuroblastoma cell line suggested that CAMK2γ is closely related to SNS activity. This evidence concerns the gene CAMK2G and neuroblastoma.