CRP and COVID-19: Moreover, a retrospective study evaluated the role of the CRP to serum albumin ratio in 272 COVID-19 patients in terms of mortality, finding an optimal cut-off above 21.5 (c-statistic of 0.72; 95% CI 0.66–0.77) [22], whereas another study that involved 3471 patients showed an optimal cut-off above 25 to be associated with mortality (OR, 1.47; 95% CI 1.19–1.82) [23].