Lactobacillus acidophilus, Bifidobacteria bifidum, and Bifidobacteria infantum promote the increased expression of mucin 2 (MUC2), zonula occludens (ZO-1), and occludin, which are an essential part of intestinal epithelial barrier integrity and have shown an association with decreased colorectal tumor incidence and volume [12]. Here, MUC2 is linked to colorectal neoplasm.