One theory in the literature suggests that the SARS-CoV-2 virus accumulates in pulmonary vessels, causing exudative vasculitis accompanied by the appearance of noncanonical monocytes expressing thrombospondin-1 and the formation of microthrombi containing myosin light chain 9 (Myl9) in the lungs of patients with severe COVID-19 [40]. This evidence concerns the gene THBS1 and COVID-19.