The DCA–VPA treatment significantly downregulated the expression of ACKR3, CCL22, CCL24, CCL4, CCR1, CCR2, CCRL2, CD209, CMKLR1, CSF1, CSF2, CSF3, CSF3R, CX3CR1, CXCL1, CXCL13, CXCL2, CXCL3, CXCL5, CXCL6, CXCR2, CXCR3, EBI3, IL10, IL12RB1, IL19, IL1A, IL1B, IL1RN, IL24, IL23A, IL27, IL27RA, IL2RA, IL6, ITGB2, JAK3, LIF, OSM, and TNFRSF14 genes of T lymphocytes of males suffering from SARS-CoV-2 infection with pneumonia. This evidence concerns the gene IL1RN and pneumonia.