As shown in Figure 7, diabetes led to a statistically significant increase in the levels of glutamate in the diabetic non-treated retinas, an effect that was attenuated by treatment with the NOX2 inhibitor, GLX7013170 (Figure 7A, *** p < 0.001 compared to control, #p < 0.05 compared to the diabetic non-treated group). The gene discussed is CYBB; the disease is diabetes mellitus.