Epigallocatechin gallate (EGCG), a major catechin found in green tea, shut down the angiogenic and proliferative capacity of breast cancer cells through the inhibition of hypoxia-inducible factor 1 subunit alpha (HIF-1α), NFκB activation, and vascular endothelial growth factor (VEGF) expression in a murine model [11,57]. The gene discussed is NFKB1; the disease is breast cancer.