GPT and injury: Qin et al. showed that tanshinone IIA (1) played a key role in the treatment of liver injury, as evidenced by the ability of tanshinone IIA (1) to significantly reduce the level of plasma glutamic pyruvic transaminase (ALT) and glutamic oxaloacetic transaminase (AST), increase the ratios of CD3+, CD4+, and CD8+ T cells, and reduce liver invasion by regulating the number of T-cell subsets in immunologically mediated liver-injured mice [95].