Rosmarinic acid (13) attenuated imiquimod (IMQ)-induced psoriasis-like inflammation in mice by decreasing IL-23 expression, inhibiting Th17-dominated inflammation, downregulating the Janus kinase 2 (Jak2)/STAT3 signaling pathway, and inhibiting keratinocyte hyperproliferation in vivo and in vitro [128]. The gene discussed is JAK2; the disease is psoriasis.