There were significantly lower levels of MSTN (80.6 pg/mL vs. 186.2 pg/mL; p = 0.0364), as well as Act A (32.1 pg/mL vs. 35.2 pg/mL; p = 0.0132) in the IBD patients with sarcopenia compared to those without sarcopenia. This evidence concerns the gene SERPINA3 and inflammatory bowel disease.