In fact, our study found no correlation between hypertension and well-known related factors with high BP in the general population, such as hyperparathyroidism, nephrocalcinosis, high FGF23 levels, obesity, or the use of nonsteroidal anti-inflammatory drugs, which XLH patients commonly use for pain control. The gene discussed is FGF23; the disease is obesity due to melanocortin 4 receptor deficiency.