WWOX and neoplasm: WWOX protein is not a typical tumor suppressor, as it participates in numerous biological events, including (i) cell survival, proliferation, differentiation, cell cycle regulation, and senescence via complicated signaling pathways [38,39,40,41,42,43,44,45], (ii) aging and neurodegeneration [22,23,46,47], (iii) apoptotic cell death [30,48,49,50,51], (iv) chromosomal DNA stability [52,53], (v) bubbling cell death [54,55,56], and (vi) cell-to-cell recognition and migration [57].