TF and venous thromboembolism: It was also demonstrated in the study of Kobayashi et al. (2021) that TF levels above or equal to 100 pg/Ml constitute an independent predictive factor for cancer-associated thromboembolism, while it was also proposed that D-dimers and microvesicle tissue factor (MV-TF) could be utilized as biomarkers for venous thromboembolism in PDAC and may facilitate the identification of patients for whom thromboprophylaxis has to be administrated [154,155].