In opposition to these results, Sári and collaborators evinced increased oxidative/nitrosative stress through the upregulation of inducible nitric oxide synthase (iNOS), downregulation of nuclear factor erythroid 2-related factor 2 (NRF2), and increased mitochondrial oxidative stress in breast cancer cells treated with IPA [45]. Here, NFE2L2 is linked to breast carcinoma.