TRG showed anti-diabetic effects in both nonobese and obese T2DM animal models by decreasing the levels of blood glucose, insulin, TNF-α, HbA1c, TC, LDL-c, TG, FFA, etc. [65] TRG could decrease the activities of intestinal a-amylase, maltase, and lipase by 36%, 52%, and 56%, respectively [6]. Here, INS is linked to type 2 diabetes mellitus.