PIK3CA and gastric cancer: As previously described, the direct targeting of the nuclear protein Forkhead box M1 (FoxM1) triggers pathways such as MEK/ERK, NF-κB, and PI3K/AKT, via mir-320d in GC cases, suggesting its tumor-suppressive properties and positioning mir-320d as a potential biomarker for cancer prognosis and treatment (Table 3) [97].