We observed a strong inverse correlation between increasing fold change in ALDH score and worse MFS (r = −0.746, p = 0.03, Figure 6C) among sorafenib/RT patients, whereas there was no significant association between increasing fold change in ALDH score and MFS (r = −0.193, p = 0.53) among STS patients treated with neoadjuvant RT monotherapy (Figure 6D). This evidence concerns the gene LDHA and telomere syndrome.