Furthermore, proteins related to cell proliferation (cyclin B1, cyclin D1, CDK4) were found to be inhibited in DLBCL due to downregulation of miR-155, which in turn led to an increased expression of pro-apoptotic proteins Bax/Bcl2 and caspase 3 [37]. Here, CASP3 is linked to diffuse large B-cell lymphoma.