No additional differences were observed using the AHI 30/h threshold (median (IQR) PD-L1/total protein 7.00 (2.60–8.85) for the AHI < 30/h group versus 5.8 (4.15–7.60) for the severe OSA group; p > 0.05) or separating patients by median T90 (median (IQR) PD-L1/total protein 8.00 (5.97–10.32) for the T90 ≤ 9% group versus 6.0 (4.65–7.80) for the T90 > 9% group; p > 0.05). Here, CD274 is linked to obstructive sleep apnea syndrome.