HMGA2 and polycystic ovary syndrome: MiR-23a-3p: Wei et al. demonstrated in their study that an overexpression of miR-23a-3p negatively targets the high-mobility group at hook 2 (HMGA2) to block the Wnt/β-catenin signaling pathway, thereby suppressing viability and promoting apoptosis in granulosa cells [41] in women with PCOS who have lower apoptosis rates of granulosa cells in their ovaries [42].