Determination of the single glycation contribution is important for comparing albumins of different types, for developing metabolic disease therapies (since glycation and/or binding to RAGE can affect the affinity of the protein for various pharmaceuticals), and for studying the phenotypic features of patients with mutated albumin (for example, the Canterbury 313Lys→Asn, Vanves 574Lys→Asn or Verona 570Glu→Lys mutations [22]). Here, ALB is linked to Other metabolic disease.