PPP2R5D and cardiac hypertrophy: Similarly, β-adrenergic receptor (βAR)-induced phosphorylation of B56δ at S573 by PKA suggests its mechanistic role in the pathogenesis of cardiac hypertrophy, and the absolute abundance of B56δ phosphorylation at S573 in mouse hearts with pressure overload-induced cardiac hypertrophy reinforces this conclusion [18].