H2A.J expression in mesenchymal type of glioblastoma is associated with Proneural-Mesenchymal Transition (PMT) and activation of Tumor Necrosis Factor—Alpha (TNF-α)/Nuclear Factor Kappa-light-chain-enhancer of activated B cells (NF-κB) pathways. This evidence concerns the gene NFKB1 and glioblastoma.