We selected subgroups belonging to each PCa type in these studies, and the correlation of HMGB2 expression and FN1, ZWINT, IGFBP3, SERPINE1, and TYMS was analyzed in AR-negative-neuroendocrine-positive (AR−/NE+) and AR-positive-neuroendocrine-negative (AR+/NE−) patients. Here, SERPINE1 is linked to posterior cortical atrophy.