All patients should conduct thorough evaluations of nephropathy (including albumin, estimated glomerular filtrate [eGFR]), neuropathy (incorporating a detailed history, temperature assessment, pinprick sensation, vibration sensation, and monofilament testing), and retinopathy (requiring a comprehensive eye examination) at the initial onset of T2D, and no later than 5 years after the diagnosis of TID, and at least annually thereafter [3,4]. This evidence concerns the gene ALB and type 2 diabetes mellitus.