Genetic testing is recommended for CPVT-susceptibility genes—RyR2, CASQ2, CALM1-3, TRDN and TECRL—in all probands with a definitive clinical diagnosis of CPVT and may be considered in individuals with idiopathic ventricular fibrillation (VF) upon identification of an adrenergic trigger. The gene discussed is RYR2; the disease is ventricular fibrillation.