This indicates that there are patients with possible ADPKD who may have mild variants in PKD1 or PKD2 or variants in other ADPKD genes such as GANAB or DNAJB11, because only 18% of patients have probably pathogenic nonsense variants in PKD1, according to Lanktree et al. [8]. Here, DNAJB11 is linked to autosomal dominant polycystic kidney disease.