In order to avoid confounding factors, we performed a new comparison of the magnitude of the change between groups by adjusting for the following variables, which had significant differences at visit 0: hypertension, type of ACS (STEMI or NSTEACS) and prescription of ACEI, beta-blockers, and P2Y12 inhibitors at discharge (Table 3). Here, P2RY12 is linked to hypertensive disorder.