IFNB1 and Hypertension: The kidney is particularly involved in IFNβ side effects with several patterns of toxicity ranging from isolated hypertension [6] to immune-mediated complications, such as podocytopathies, glomerulonephritis, acute tubular necrosis, (acute and chronic) tubulo-interstitial nephritis, or thrombotic microangiopathy (TMA) [7,8,9].