NPPB and hydrops fetalis: Measurement of circulating levels of natriuretic peptides (NPs), in particular, B-type natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP), represents a valuable biochemical tool for establishing a diagnosis of HF, both in HFrEF and in HF with preserved ejection fraction (HFpEF) [1,3,15,16].