However, the study may be enhanced by assessing the radiopharmaceutical biodistribution through different models, including patient-derived xenograft (PDX) models or orthotopic genetically-engineered mouse models (GEMM) of CCK2R+ gastrointestinal tumors, which are considered more accurate and closely mimic the human cancer counterparts [61,62]. Here, CCKBR is linked to digestive system neoplasm.