The stimulation of beta 2 adrenoreceptors causes the suppression of macrophages involved in anti-tumor defense and the stimulation of macrophages that favor tumor growth via chitinase-3-like protein 1 (CHI3L1), the transcription factor GATA3, or tumor suppressor protein p 53 (TP53) [41,42,43]. The gene discussed is CHI3L1; the disease is neoplasm.