Shousha et al. [67] studied the impact of LSV and some components of tumorigenic cells, called cancer stem cells (CSCs), including epithelial cell adhesion molecule (EpCAM) and cytokeratin-19 (CK-19) markers, to predict HCC recurrence and their impact on the clinical outcome of HCC and overall survival. This evidence concerns the gene KRT19 and hepatocellular carcinoma.