No association was found between AD development and exposure to aluminum in any of the forms except for organic monomeric aluminum after the data were adjusted for genetic characteristics, such as the presence of the ApoE-e4 allele and cases of dementia or AD among first-degree relatives (odds ratio (OR) 2.67; 95% confidence interval (CI) 1.04–6.90, p = 0.01) [8]. Here, APOE is linked to Alzheimer disease.