Following a meta-analysis performed by Liu et al. on 3753 subjects, the results showed the possibility that XPD 2251A>C may be a risk factor for AML, especially for Caucasian patients with acute leukemia (OR = 1.23; 95% CI = 1.03–1.46) [59]. The gene discussed is ERCC2; the disease is acute myeloid leukemia.