In urine, dipstick albuminuria together with urine microscopy have been a useful tool for a long time, while the urine levels of KIM-1, NGAL (neutrophil gelatinase-associated lipocalin), CCL-14 (chemokine ligand 14), TIMP-2 (tissue inhibitor of metalloproteinase 2), PTGS2 (Prostaglandin endoperoxide Synthase 2) and sTREM-1 (soluble triggering receptor expressed on myeloid cells 1) are being tested as potential urinary biomarkers of SA-AKI [5,52,53,54]. The gene discussed is PTGS2; the disease is acute kidney injury.