KEAP1 and neoplasm: The patient’s genetic investigation with whole-exome sequencing (WES) was per-formed to assess the following genes that are involved in squamous tumor development: COL17A1 (collagen type XVII alpha 1 chain gene), CYLD (gene which encodes a tumor suppressor of deubiquitinates called cylindromatosis with a predominant role in the regulation of Nuclear Factor-κB (NF-κB)), DICER1 (dicer 1, ribonuclease III gene), EWSR1 (gene whose product is an RNA-binding protein), KEAP1 (gene that encodes the kelch-like ECH-associated protein 1), TGFBI, TGFBR1, and TGFBR2.